The status of antibiotic resistance of Shigellosis spp. isolated in Vietnam during 1995 - 2016

Abstract

Shigellosis is an acute infection of the intestines caused by Shigella bacteria with diverse clinical manifestations. Currently, this disease is still an important health issue in the community, especially concerned about the increase in antibiotic resistance of Shigella spp. This study was conducted to determine the serotype and antibiotic susceptibility of Shigella spp. over 13 isolated samples in some diarrhea epidemics in some provinces in Vietnam from 1995 to 2016. The results showed that S. flexneri was the main species accounting for 8/13 (61.5%) and S. sonnei accounted for 5/13 (38.5%). 12/13 (92.3%) samples had antibiotic resistance, of which the resistance to 6 antibiotics was 7.7% (1/13 isolates), and the resistance to 5 antibiotics was 30.8% (4/ 13 isolates), and the resistance to 4 antibiotics was 23.1% (3/3 of 13 isolates). Some antibiotics such as ciprofloxacin, gentamicin were still 100% sensitive to Shigella isolated while the lowest susceptibility rate was as sulfamethoxazole/trimethoprim (23.1%) and tetracycline (30.8%). The rate of antibiotic resistance of Shigella spp. was high. It is necessary to continue to monitor the antibiotic resistance of Shigella strains to contribute to effective treatment and prevention of disease.