Seroprevalence of Zikavirus infection in the general population in Hanoi, Vietnam

Các tác giả

  • Ngu Duy Nghia National Institute of Hygiene and Epidemiology, Hanoi
  • Tran Anh Tu National Institute of Hygiene and Epidemiology, Hanoi
  • Ngo Huy Tu National Institute of Hygiene and Epidemiology, Hanoi
  • Pham Thi Cam Ha National Institute of Hygiene and Epidemiology, Hanoi
  • Tran Duc Linh National Institute of Hygiene and Epidemiology, Hanoi
  • Nguyen Hong Son National Institute of Hygiene and Epidemiology, Hanoi
  • Nguyen Thi Thu Thuy National Institute of Hygiene and Epidemiology, Hanoi
  • Le Thi Hien Thu National Institute of Hygiene and Epidemiology, Hanoi
  • Pham Thi Thu Hang National Institute of Hygiene and Epidemiology, Hanoi
  • Vu Thi Bich Hau National Institute of Hygiene and Epidemiology, Hanoi
  • Do Thi Hong Hien World Health Organization, Hanoi
  • Orla Condell World Health Organization, Hanoi
  • Satoko Otsu World Health Organization, Hanoi
  • F Hasebe Nagasaki University, Japan
  • Nguyen Cong Khanh National Institute of Hygiene and Epidemiology, Hanoi
  • Tran Nhu Duong National Institute of Hygiene and Epidemiology, Hanoi

DOI:

https://doi.org/10.51403/0868-2836/2021/492

Từ khóa:

Zika, Seroprevalence, Hanoi, Vietnam

Tóm tắt

Since 2017, ZIKV infection was reported in many provinces in Vietnam, except in Hanoi. To determine the existence of ZIKV infection in this city, a seroprevalence survey was conducted by collecting samples from healthy people living in Hanoi (12/2018 – 2/2019). The specimens (500 people) were tested for anti-ZIKV immunoglobulin M (IgM), anti-DENV and anti-JEV IgM using enzyme-linked immunosorbent assay (ELISA). Plaque-reduction neutralization test (PRNT) for ZIKV was conducted for all samples, and PRNT for DENV and JEV among those ZIKV positive by PRNT. Among 500 participants, using ELISA detecting ZIKV IgM antibodies, we identified 11 (2.2%) probable ZIKV infection. ZIKV infection probably occurred in people aged above 50 years old, female and living in high DENV endemic districts. ZIKV PRNT with titers  1:40 were detected in 15 (3%) cases. However, we could not confirm ZIKV infection among these 15 cases due to cross reaction with 4 subtypes of DENV.

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Đã Xuất bản

18-02-2022

Cách trích dẫn

Nghia, N. D. ., Tu, T. A. ., Tu, N. H. ., Ha, P. T. C. ., Linh, T. D. ., Son, N. H. ., Thuy, N. T. T. ., Thu, L. T. H. ., Hang, P. T. T. ., Hau, V. T. B. ., Hien, D. T. H. ., Condell, O. ., Otsu, S. ., Hasebe, F. ., Khanh, N. C., & Duong, T. N. . (2022). Seroprevalence of Zikavirus infection in the general population in Hanoi, Vietnam. Tạp Chí Y học Dự phòng, 31(10), 40–45. https://doi.org/10.51403/0868-2836/2021/492

Số

T. 31 S. 10 (2021): Số tiếng anh

Chuyên mục

Bài báo nghiên cứu gốc

Giấy phép

Giấy phép xuất bản số: 150/GP-BTTTT cấp ngày 8/5/2014;
Giấy phép hoạt động báo chí điện tử số 322/GP-BTTTT cấp ngày 15/6/2016.

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