The neutralization antibodies of SARS-CoV-2 during COVID-19 outbreak in Da Nang, Vietnam, July - August 2020

Các tác giả

  • Le Thi Thanh National Institute of Hygiene and Epidemiology, Hanoi
  • Hoang Vu Mai Phuong National Institute of Hygiene and Epidemiology, Hanoi
  • Nguyen Le Khanh Hang National Institute of Hygiene and Epidemiology, Hanoi
  • Vuong Duc Cuong National Institute of Hygiene and Epidemiology, Hanoi
  • Nguyen Phuong Anh National Institute of Hygiene and Epidemiology, Hanoi
  • Ung Thi Hong Trang National Institute of Hygiene and Epidemiology, Hanoi
  • Tran Thi Thu Huong National Institute of Hygiene and Epidemiology, Hanoi
  • Nguyen Vu Son National Institute of Hygiene and Epidemiology, Hanoi
  • Le Thi Quynh Mai National Institute of Hygiene and Epidemiology, Hanoi

DOI:

https://doi.org/10.51403/0868-2836/2023/1473

Từ khóa:

Seroprevalence, SARS-CoV-2, neutralizing antibodies, Da Nang

Tóm tắt

Beside molecular tests (realtime RT-PCR) which known as the golden key for SARS-CoV-2 confirmation, antibody test can be used to determine the responses in human antibody to SARS-CoV-2 and the result of plaque reduction neutralization test (PRNT) could identify the people who have been exposed with the SARS-CoV-2 and carried the neutralization antibody. Total 9936 samples were collected in 3 groups healthcare workers, inpatients (not related to COVID-19 before) and community in Da Nang city during July-August 2020. These cross sectional results showed that the rate of neutralization antibody in three groups in this research was 0.2%, in that, 0.1% in community, 0.2% in inpatient and 0.4% in healthcare workers. Follow-up study with 1253 paired sera of healthcare workers, the rate of SARS-CoV-2 neutralization antibody was determined as 2.1%. A downward trend of this neutralization antibody overtime has been shown in the study.

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Đã Xuất bản

20-03-2024

Cách trích dẫn

Thanh, L. T. ., Phuong, H. V. M. ., Hang, N. L. K. ., Cuong, V. D. ., Anh, N. P. ., Trang, U. T. H. ., Huong, T. T. T. ., Son, . N. V. ., & Mai, L. T. Q. . (2024). The neutralization antibodies of SARS-CoV-2 during COVID-19 outbreak in Da Nang, Vietnam, July - August 2020. Tạp Chí Y học Dự phòng, 33(8), 16–23. https://doi.org/10.51403/0868-2836/2023/1473

Số

T. 33 S. 8 (2023): Số tiếng anh

Chuyên mục

Bài báo nghiên cứu gốc

Giấy phép

Giấy phép xuất bản số: 150/GP-BTTTT cấp ngày 8/5/2014;
Giấy phép hoạt động báo chí điện tử số 322/GP-BTTTT cấp ngày 15/6/2016.

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