Molecular epidemilogy of respiratory syncytial virus

Abstract

Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract diseases in both young children and the elderly people. Although the virus was first isolated in 1955, there is no effective vaccine has not been developed. The researches have been done to develop vaccines in children, pregnant women, the elder and adults, but these candidate vaccines are not yet got license for production. Genetic diversity, temporal and geographic characteristics, dependence on seasonality and humidity, and the possibility of reinfection are factors that make molecular epidemiological models of RSV susceptible complex. This review conducted recently researches not only in the world but also in Vietnam in order to provide the trends and future development prospects of research RSV.