Result of mandibular distraction osteogenesis to treat airway obstruction in infants with severe Pierre Robin Syndrome at the National Children's Hospital, 2019 – 2023

Abstract

Our research focuses on describing results of mandibular distraction surgery (MDO) in the treatment of severe Pierre Robin Sequence (PRS) at the National Children’s Hospital from 2019 to 2023. This method has been used as an alternative to previous tracheostomy surgery. The study subjects were patients with severe PRS, severe dyspnea due to obstruction, difficulty sucking, need feeding support, and have a large maxillary-mandibular gap greater than 10mm. The study was designed as a noncontrolled clinical intervention with pre-post evaluation with 102 patients from 2 weeks to 6 months of age followed for a period of 6 to 36 months. The results showed that after MDO, the success rate in the study was 95.1%. Airway size on CT scanner has increased 4.16 times before surgery. The success rate for oral feeding and nutrition via oral route post-surgery was 82.4%. Mandibular distraction osteogenesis emerges as a safe and effective method in treating airway obstruction in infants with severe Pierre Robin Syndrome, avoiding tracheostomy. However, proper patient selection, surgical planning, and to limit complications.