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Page: 22
Volume XXVI, Issue 3(176) 2016
Seroprevalence of Histoplasmosis in lung infection patients in Hanoi hospitals
Author: Hoang Thi Thu Ha, Hideaki Ohno, Luong Minh Hoa, Nguyen Thuy Tram, Pham Thanh Hai, Nguyen Thai Son, Nguyen Van Tien, Duong Ngoc Thuy, Nguyen Tran Hien and Dang Duc Anh
Summary:
Histoplasmosis, a fungal infection caused by Histoplasma capsulatum (H.capsulatum) that is a severe biohazard pathogen. H.capsulatum occurs most commonly in America and Africa, but the organism exists in many diverse areas around the world. Histoplasmosis can be acquired from the soil contaminated with bird/bat or chicken droppings. The most common clinical presentation is asymptomatic. However, the symptoms of acute or epidemic histoplasmosis are high fever, cough, and asthenia. High risk groups include immunocompromised persons (e.g., persons with cancer, transplant recipients, persons with HIV infection). A seroprevalence study among lung infection patients in Bach Mai and 103 Military Hospitals in Hanoi was conducted during 2012-2013. A proportion of histoplasmosis has been identified from lung infection patients by an indirect ELISA (HistoplasmaDxSelect™ kit - USA). The results showed that H.capsulatum antibodies were detected in 18% (26/144) of patients. Among them, 57.7% (15/26) were HIV positive patients, and 65.4% (17/26) were chronic pulmonary patients. Because the proportion of Histoplasmosis in lung infection patients of this study is very high, it could be confirmed that H.capulatum has been presented in Vietnam. This is the first report of the seroprevalence of histoplasmosis in Hanoi. However, a source of the pathogen is still a challenge and need to be demonstrated in further studies
Keywords:
Histoplasmosis, lung infection patient, ELISA, seroprevalence
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Happy New Year 2019! Year of the Pig
The Vietnam Journal of Preventive Medicine wish all readers with healthy, happiness and prosperity in the year of the Pig. Happy New Year 2019
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